Medics warn against growing resistance of anti fungal drugs in pregnant women

Doctors have warned of an increase in resistance to common antifungal drugs used for the treatment of infections like candidiasis. Drug-resistant tuberculosis is also a growing phenomenon, while malaria parasites also are becoming resistant to once-effective first-line anti-malarial treatments. The World Health Organisation has already warned that over four million Africans a year could die as…

First real-world study reports effectiveness of BBV152 against symptomatic COVID-19 in India

Study includes more than 2,700 healthcare workers in Delhi, India, who were symptomatic and underwent RT-PCR testing for COVID-19. Findings suggest 50% vaccine effectiveness against symptomatic COVID-19 after two doses of BBV152. This vaccine effectiveness is lower than the vaccine efficacy suggested by Bharat Biotech’s phase 3 randomised control trial results. The authors note several…

COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020, with women and younger people most affected.

First global estimates of impact of the COVID-19 pandemic on mental health in 2020 suggests additional 53 million cases of major depressive disorder and 76 million cases of anxiety disorders were due to the pandemic. Women and younger people were the most affected by major depressive disorder and anxiety disorders in 2020. Countries hit hardest…

Treatment of COVID-19 with fluvoxamine reduces risk of prolonged hospitalisation, finds largest trial to date

The fluvoxamine arm of the TOGETHER trial, a randomised adaptive platform trial investigating the efficacy of repurposed treatments for COVID-19 among high-risk Brazilian adult outpatients, is the largest trial of the SSRI fluvoxamine as a COVID-19 treatment to date. Of the 741 participants who were treated in an emergency setting for COVID-19 after receiving fluvoxamine,…

COVID-19 vaccines lower risk of infection with delta variant, but infection can still be passed on in household settings

Study of 621 people in the UK with mild COVID-19 infections found that people who received two vaccine doses could still pass the infection on to vaccinated and unvaccinated household members. The analysis found that 25% of vaccinated household contacts tested positive for COVID-19 compared with 38% of unvaccinated household contacts. The infectiousness of vaccinated…