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Fentanyl is a particularly powerful synthetic opioid. Diverted from its original medical use, it has become a deadly drug responsible for three-quarters of overdose deaths in the United States. Yet, our knowledge of the impact of opioids on the brain remains incomplete. By deciphering the neuronal mechanisms involved, a team from the University of Geneva (UNIGE) has discovered that…
Schizophrenia, which affects up to 1% of the population, is a neuropsychiatric disorder characterized by multiple symptoms. One of the most common, and for which there is no treatment, is apathy and lack of motivation. By comparing neural activation between a group of patients and a control group during a reward-based game, a team from the University of Geneva (UNIGE)…
High-protein diets, known as ‘‘Paleolithic diets’’, are popular. Using mouse models, scientists at the University of Geneva (UNIGE) have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma. These results, published…